ScienceSigns of Creation

PROTEINS CHALLENGE COINCIDENCE (EVOLUTION)

Proteins are giant molecules consisting of amino acids arranged in a particular sequence in certain quantities and structures. These molecules constitute the building blocks of a living cell. The simplest is composed of 50 amino acids; but there are some proteins that are composed of thousands of amino acids. The absence, addition, or replacement of a single amino acid in the structure of a protein in living cells, each of which has a particular function, causes the protein to become a useless molecular heap. Incapable of demonstrating the “accidental formation” of amino acids, the theory of evolution founders on the point of the formation of proteins.

We can easily demonstrate, with simple probability calculations anybody can understand, that the functional structure of proteins can by no means come about by chance.

There are twenty different amino acids. If we consider that an average-sized protein molecule is composed of 288 amino acids, there are 10300 different combinations of acids. Of all of these possible sequences, only “one” forms the desired protein molecule. The other amino-acid chains are either completely useless or else potentially harmful to living things. In other words, the probability of the coincidental formation of only one protein molecule cited above is “1 in 10300”. The probability of this “1” occurring out of an “astronomical” number consisting of 1 followed by 300 zeros is for all practical purposes zero; it is impossible. Furthermore, a protein molecule of 288 amino acids is rather a modest one compared with some giant protein molecules consisting of thousands of amino acids. When we apply similar probability calculations to these giant protein molecules, we see that even the word “impossible” becomes inadequate.

If the coincidental formation of even one of these proteins is impossible, it is billions of times more impossible for approximately one million of those proteins to come together by chance in an organised fashion and make up a complete human cell. Moreover, a cell is not merely a collection of proteins. In addition to proteins, cells also include nucleic acids, carbohydrates, lipids, vitamins, and many other chemicals such as electrolytes, all of which are arranged harmoniously and with design in specific proportions, both in terms of structure and function. Each functions as a building block or component in various organelles.

As we have seen, evolution is unable to explain the formation of even a single protein out of the millions in the cell, let alone explain the cell.

Prof. Dr. Ali Demirsoy, one of the foremost authorities of evolutionist thought in Turkey, in his book Kalitim ve Evrim (Inheritance and Evolution), discusses the probability of the accidental formation of Cytochrome-C, one of the essential enzymes for life:

The probability of the formation of a Cytochrome-C sequence is as likely as zero. That is, if life requires a certain sequence, it can be said that this has a probability likely to be realised once in the whole universe. Otherwise, some metaphysical powers beyond our definition should have acted in its formation. To accept the latter is not appropriate to the goals of science. We therefore have to look into the first hypothesis.11
After these lines, Demirsoy admits that this probability, which he accepted just because it was “more appropriate to the goals of science”, is unrealistic:
The probability of providing the particular amino acid sequence of Cytochrome-C is as unlikely as the possibility of a monkey writing the history of humanity on a typewriter – taking it for granted that the monkey pushes the keys at random.12
The correct sequence of proper amino acids is simply not enough for the formation of one of the protein molecules present in living things. Besides this, each of the twenty different types of amino acid present in the composition of proteins must be left-handed. Chemically, there are two different types of amino acids called “left-handed” and “right-handed”. The difference between them is the mirror-symmetry between their three dimensional structures, which is similar to that of a person’s right and left hands. Amino acids of either of these two types are found in equal numbers in nature and they can bond perfectly well with one another. Yet, research uncovers an astonishing fact: all proteins present in the structure of living things are made up of left-handed amino acids. Even a single right-handed amino acid attached to the structure of a protein renders it useless.
Let us for an instant suppose that life came into existence by chance as evolutionists claim. In this case, the right and left-handed amino acids that were generated by chance should be present in nature in roughly equal amounts. The question of how proteins can pick out only left-handed amino acids, and how not even a single right-handed amino acid becomes involved in the life process is something that still confounds evolutionists. In the Britannica Science Encyclopaedia, an ardent defender of evolution, the authors indicate that the amino acids of all living organisms on earth and the building blocks of complex polymers such as proteins have the same left-handed asymmetry. They add that this is tantamount to tossing a coin a million times and always getting heads. In the same encyclopaedia, they state that it is not possible to understand why molecules become left-handed or right-handed and that this choice is fascinatingly related to the source of life on earth.13

It is not enough for amino acids to be arranged in the correct numbers, sequences, and in the required three-dimensional structures. The formation of a protein also requires that amino acid molecules with more than one arm be linked to each other only through certain arms. Such a bond is called a “peptide bond”. Amino acids can make different bonds with each other; but proteins comprise those and only those amino acids that join together by “peptide” bonds.

Research has shown that only 50 % of amino acids, combining at random, combine with a peptide bond and that the rest combine with different bonds that are not present in proteins. To function properly, each amino acid making up a protein must join with other amino acids with a peptide bond, as it has only to be chosen from among the left-handed ones. Unquestionably, there is no control mechanism to select and leave out the right-handed amino acids and personally make sure that each amino acid makes a peptide bond with the other.

Under these circumstances, the probabilities of an average protein molecule comprising five hundred amino acids arranging itself in the correct quantities and in sequence, in addition to the probabilities of all of the amino acids it contains being only left-handed and combining using only peptide bonds are as follows:

– The probability of being in the right sequence = 1/20500 =1/10650

– The probability of being left-handed = 1/2500 =1/10150

– The probability of combining using a “peptide bond” = 1/2499 =1/10150

TOTAL PROBABILITY = 1/10950 that is, “1” probability in 10950

As you can see above, the probability of the formation of a protein molecule comprising five hundred amino acids is “1” divided by a number formed by placing 950 zeros after a 1, a number incomprehensible to the human mind. This is only a probability on paper. Practically, such a possibility has “0” chance of realisation. In mathematics, a probability smaller than 1 over 1050 is statistically considered to have a “0” probability of realisation.

While the improbability of the formation of a protein molecule made up of five hundred amino acids reaches such an extent, we can further proceed to push the limits of the mind to higher levels of improbability. In the “haemoglobin” molecule, a vital protein, there are five hundred and seventy-four amino acids, which is a much larger number than that of the amino acids making up the protein mentioned above. Now consider this: in only one out of the billions of red blood cells in your body, there are “280,000,000” (280 million) haemoglobin molecules. The supposed age of the earth is not sufficient to afford the formation of even a single protein, let alone a red blood cell, by the method of “trial and error”. The conclusion from all this is that evolution falls into a terrible abyss of improbability right at the stage of the formation of a single protein.

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